Inside Noom’s Proactive Health Microdose GLP-1Rx Program: Understanding the biomarkers

Most people visit the doctor once a year, get a set of lab results, and move on. Numbers like cholesterol, triglycerides, or HbA1c show up on a page—but what do they actually say about how your body is aging?

Your biomarkers are the body’s dashboard. They reflect how your metabolism, heart, inflammation levels, hormones, organs, and nutrient stores are performing right now. When tracked over time, they can reveal how fast you’re aging biologically and, more importantly, where small changes could improve your health, energy, and resilience. The goal isn’t just to live longer, but to live better.

For some of these markers, annual testing isn’t enough. As you age or begin changing habits, weight, or metabolic health, a more proactive approach helps you see meaningful trends instead of one-off snapshots. That’s why we created Noom’s Proactive Health Microdose GLP-1^Rx Program, which supports more comprehensive, ongoing monitoring of the markers most closely tied to healthspan.

We’ve identified 17 biomarkers that give the clearest picture of how your body is aging. They span four core pillars of health and show where targeted action can make the biggest difference. Together, these markers show how your body is aging on the inside and where targeted action can make the biggest difference.

4 pillars of biological age  

Your body doesn’t age in separate pieces. All your systems work together, and your biomarkers reflect that. In fact, research shows that multisystem biomarkers are stronger predictors of aging than single tests because they capture how interconnected your health really is. 

We provide 17 biomarker-based health insights that fall within four core pillars that research shows are important for health.

Here’s how each pillar plays a role:

1. Metabolic health: Your metabolism determines how well your body uses food for fuel. When blood sugar and insulin are well regulated, you have steadier energy, less inflammation, and a lower risk of weight gain and metabolic disease. When this system struggles, aging tends to accelerate across many parts of the body.
2. Cardiovascular health: Your heart and blood vessels deliver oxygen and nutrients to every cell. Healthy circulation keeps tissues flexible, supports brain function, and protects long-term heart health. When these markers drift, plaque can build up and blood flow becomes less efficient, often years before symptoms appear.
3. Inflammation & cellular stress: Inflammation is part of normal healing, but when you have chronic inflammation, it quietly damages blood vessels, organs, and tissues. Chronic inflammation increases the risk of heart disease, metabolic issues, and faster biological aging, even if you feel fine on the surface.
4. Hormonal health: Hormones act as your body’s control signals. They influence energy, muscle and bone strength, mood, sleep, and metabolism. Hormone patterns differ between males and females and change significantly with age—especially during midlife, perimenopause, and menopause—so tracking them helps explain shifts that diet or exercise alone may not account for.

These pillars are closely connected. Better metabolic health can improve your cardiovascular numbers, while managing stress can lower inflammation. A small improvement in one pillar often creates positive changes across the others.

Noom’s Proactive Health Microdose GLP-1^Rx Program

Longevity biomarkers work best when you track them regularly to understand how your body is performing over time. Consistent testing helps you spot early changes, connect patterns to your habits, and adjust before small issues become bigger problems.

Noom’s Proactive Health Microdose GLP-1^Rx Program was built around this idea. It pairs regular lab testing, clinical support, and low-dose GLP-1 support to help regulate blood sugar and appetite, reduce inflammation, and support steady energy.

Your lab bundle: The tests that matter most

Noom’s lab bundle includes 17 biomarker-based health insights. The test tracks:

• Metabolic markers
  • Hemoglobin A1c (HbA1c)
  • Triglycerides
  • Triglycerides/HDL ratio
    
• Cardiovascular markers
  • Apolipoprotein B (ApoB) 
  • Lipoprotein (a) (Lp(a))
  • Full cholesterol panel
    • LDL
    • High-Density Lipoprotein (HDL-C)
    • Total cholesterol
  • Total Cholesterol/HDL-C ratio
  • LDL-C/ApoB ratio
• Inflammation markers
  • High-Sensitivity C-Reactive Protein (hs-CRP)
  • Vitamin D
  • Vitamin B12
• Hormonal indicators
  • Total Testosterone
  • Estradiol (E2)
  • Dehydroepiandrosterone sulfate (DHEA-S)
  • LH

This comprehensive approach helps catch health changes early when they’re easier to address.

Making your results count

Regular tracking helps you see trends that can be translated into real changes that improve your health. Noom brings these lab results into the app so you can understand how nutrition, movement, sleep, and medication affect your markers over time.

Together, the structured labs, microdose GLP-1 protocol, and lifestyle guidance give you a clearer view of your biological age and a practical way to act on your results. Let’s take a look at what you can learn from your biomarkers.

Metabolic health 

Hemoglobin (HbA1c), triglycerides, and TG/HDL ratio are the three core biomarkers that offer the clearest picture of your metabolic health.

Hemoglobin A1c (HbA1c)

Hemoglobin A1c (HbA1c) is a blood test that shows your average blood sugar over the past two to three months. Doctors use it often in diabetes care because it gives a clearer picture than a single fasting reading. When this number starts creeping up, it means sugar has been staying in your bloodstream longer than it should. 

Over time, this can lead to type 2 diabetes, which is associated with cardiovascular disease, kidney disease, and even a shorter life. You won’t feel high HbA1c, which is why it’s checked during routine physicals. It helps catch blood sugar issues early, before symptoms become more noticeable.

What to know:

• Healthy levels:
  • Standard ranges are the same for both men and women:
    • Below 5.7% is considered normal
    • 5.7–6.4% signals prediabetes
    • 6.5% or higher is used to diagnose diabetes. 
    • Many doctors aim for 5.0–5.2% in otherwise healthy adults, since lower values within the normal range are linked with better long-term health when blood sugar is stable.
• How to improve it: Limit ultra-processed foods and refined sugar, eat more fiber, move your body daily (even short walks help), and get quality sleep.
• Treatment: For medical treatment, commonly used medications include metformin, GLP-1s (like semaglutide), SGLT2 inhibitors, and DPP-4 inhibitors, depending on your health history and your clinician’s plan. Microdose GLP-1 support may help steady blood sugar swings as you build healthier food, movement, and sleep routines.

Triglycerides (TG)

Triglycerides are the main form of fat your body stores for later use. After you eat, your body converts extra calories, especially from sugars and refined carbohydrates, into triglycerides and sends them into your bloodstream for transport and storage. 

When levels stay high over time, it can point to insulin resistance, more inflammation, and higher cardiovascular risk. Triglycerides are tested alongside cholesterol in a standard lipid panel, which is why they show up in most annual check-ups.

What to know:

• Healthy levels: Clinicians usually interpret triglyceride levels using the following categories:
  • Normal: <150 mg/dL
  • Borderline high: 150–199 mg/dL
  • High: 200–499 mg/dL
  • Very high: ≥500 mg/dL
  • These targets come from major cardiovascular guidelines and help clinicians assess metabolic and heart health risk.
• How to improve it: Reducing added sugars and refined carbs, limiting alcohol, and adding omega-3–rich foods (like salmon, sardines, or flaxseeds) can help lower triglycerides. Regular exercise, weight management, and improved sleep also support healthier levels. 
• Treatment: For some people, medications like statins, fibrates, or niacin may be recommended. 

Triglycerides/HDL-C ratio

The triglyceride-to-HDL cholesterol ratio (TG/HDL-C) is calculated from a standard lipid panel and gives extra insight into insulin resistance and cardiovascular risk. Higher ratios have been linked to greater insulin resistance.

What to know: 

• Healthy levels: There are no universal guideline cutoffs for TG/HDL-C, but research often uses similar ranges to describe risk. In practice, many clinicians and researchers consider a ratio below 2.0 (using mg/dL units) as favorable, 2.0–3.5 as a moderate-risk range, and above 3.5 as a sign of higher cardiometabolic risk, especially when other risk factors (like abdominal obesity or prediabetes) are present.
• How to improve it: Anything that lowers triglycerides and supports healthy HDL levels usually improves the TG/HDL-C ratio. 
• Treatment: There’s no medication that targets the TG/HDL-C ratio on its own, but clinicians often focus on the components driving it. Depending on your overall risk profile, that may include lifestyle and dietary modifications, medications, like statins, fibrates, or prescription omega-3 therapy to reduce triglyceride-rich lipoproteins and atherogenic particles. GLP-1s can also improve triglycerides and other lipid markers as part of their broader effects on glucose control, weight, and cardio health.

Cardiovascular health 

The biomarkers that give the clearest picture of cardiovascular aging are Apolipoprotein B (ApoB), Lipoprotein(a), and the full lipid panel (LDL, HDL, Total cholesterol, triglycerides), Chol/HDL ratio, and LDL-C/ApoB ratio.

Apolipoprotein B (ApoB)

Apolipoprotein B (ApoB) is the main protein found on the cholesterol-carrying particles that can enter your artery walls and form plaque. Each of these particles carries one ApoB protein, so measuring ApoB tells you how many plaque-forming particles are actually circulating in your blood. 

A study shows that apolipoprotein B (ApoB) and the ApoB/ApoA1 ratio are actually stronger predictors of cardiovascular disease than regular cholesterol numbers. This makes ApoB one of the most accurate markers of cardiovascular risk.

What to know:

• Healthy levels: Most labs consider ApoB levels within the following ranges to be normal:
  • Males: 66 to 113 mg/dL
  • Females: 60 to 117 mg/dL
• How to improve it: Increase fiber intake, prioritize whole foods, add regular aerobic exercise, and reduce refined carbs and added sugars. Consistent lifestyle changes can meaningfully lower ApoB for many people. 
• Treatment: Many people also benefit from medications like statins or ezetimibe.

Lipoprotein(a) [Lp(a)]

Lipoprotein(a), or Lp(a), is a type of cholesterol particle you inherit from your parents. Higher Lp(a) levels can raise your lifetime risk of plaque buildup, heart disease, and stroke. Unlike other cholesterol markers, Lp(a) doesn’t respond to diet, exercise, or most medications, which is why one test can tell you a lot about your long-term cardiovascular risk.

What to know:

• Healthy levels: Most experts agree that lower Lp(a) is better. Many US lipid specialists consider levels below 10 mg/dL to be low risk. Large international studies often use higher cutoffs, showing that cardiovascular risk rises more clearly once Lp(a) climbs above about 30 mg/dL or 125 nmol/L. 
• How to improve it: You can’t lower Lp(a) itself through lifestyle changes, but you can lower your overall cardiovascular risk by focusing on the biomarkers you can influence, like ApoB, triglycerides, fasting insulin, inflammation, and blood pressure. Improving metabolic health, staying active, and keeping LDL low with clinician-guided therapies can help offset the added risk from elevated Lp(a). 

Standard lipid panel (LDL, HDL, Total cholesterol, Triglycerides)

A standard lipid panel is the cholesterol test most people get at their annual checkup. It measures the main fats circulating in your bloodstream and helps show how well your body is moving, storing, and clearing them. High LDL, low HDL, or elevated triglycerides can signal early stress on your heart and blood vessels, and these shifts often appear long before symptoms do. 

What to know:

• Healthy levels: Typical healthy ranges look like this:
  • Total cholesterol: Below 200 mg/dL
  • HDL: Above 40 mg/dL for men and above 50 mg/dL for women (higher is better)
  • LDL: Below 100 mg/dL for most adults; below 70 mg/dL for people with heart disease
  • Triglycerides: Below 150 mg/dL
• How to improve it: Your lipid panel improves when your liver has less fat to package and send into the bloodstream. Eating more fiber-rich foods helps pull cholesterol out of circulation. Cutting back on added sugars and ultra-processed foods keeps triglycerides from rising. Regular aerobic activity boosts HDL (the “good” cholesterol) and helps your body clear LDL more efficiently. Limiting alcohol reduces the liver’s workload, which can lower triglycerides.
• Treatment: When lifestyle changes aren’t enough, medications can help. Statins help reduce LDL by slowing down cholesterol production or improving how cholesterol is cleared. Ezetimibe works by blocking cholesterol absorption so the body clears more LDL from the bloodstream.

Total cholesterol/HDL ratio

The total cholesterol to HDL ratio helps show how balanced your cholesterol is overall, or how much cholesterol can build up in arteries versus how much HDL is available to clear it. Research shows this ratio can be a stronger predictor of heart disease than total cholesterol alone. Lower numbers generally mean lower cardiovascular risk.

What to know:

• Healthy levels: Most clinicians aim for a ratio under 4, with under 3.5 considered a more protective range. These cutoffs align with guidance from major medical centers and large population studies.
• How to improve it: Lowering LDL and supporting healthy HDL is the most effective way to improve the ratio. Eating more fiber-rich whole foods, reducing saturated fats, and moving your body daily all help shift cholesterol in a healthier direction, and heart-healthy patterns like the Mediterranean diet improve both sides of the equation.
• Treatment: Medications that lower LDL—like statins or ezetimibe—can improve the ratio when lifestyle changes aren’t enough. Your clinician will choose treatments based on your overall heart-health risk.

LDL-C/ApoB ratio

The LDL-C/ApoB ratio helps show how many of your LDL particles are small and dense (less ideal) versus larger and less atherogenic. A lower ratio often means more small, dense LDL particles—something research links to higher cardiovascular risk. It’s a helpful add-on marker when you want a clearer picture beyond standard LDL numbers.

What to know:

• Healthy levels: There’s no universally agreed-upon clinical cutoff, but many lipid researchers consider higher ratios more favorable because they suggest fewer small, dense LDL particles. Lower ratios may signal a more atherogenic profile, especially when ApoB is elevated.
• How to improve it: Anything that reduces ApoB (the number of LDL particles) improves this ratio. Heart-healthy eating patterns, weight reduction when appropriate, regular movement, and cutting back on saturated fats can all help shift LDL particles toward a healthier pattern.
• Treatment: Most treatments that lower ApoB—such as statins, ezetimibe, or PCSK9 inhibitors—also improve the LDL-C/ApoB ratio by reducing LDL particle number. Your clinician will focus on overall risk, but lifestyle changes remain the foundation.

Inflammation & cellular stress

These markers help you see how well your body is managing everyday inflammation, recovery, and energy production. In this category, hs-CRP serves as an inflammation marker, while vitamin D and vitamin B12 are key nutrients that support immune balance, energy metabolism, and overall cellular health. Together, they highlight early signs of strain so you can course-correct before bigger issues develop.

High-sensitivity C-reactive Protein (hs-CRP)

Hs-CRP is a blood test that measures very small amounts of C-reactive protein, a substance your liver releases whenever your body is inflamed. Inflammation can come from many places—an infection, an injury, autoimmune disease, or long-term stress on your heart and blood vessels. You can’t feel this inflammation happening, which is why hs-CRP is useful: it picks up silent changes that a standard CRP test may miss.

Doctors often use hs-CRP to understand your risk for heart disease, because higher levels are linked to a greater chance of heart attack or repeat heart attack. It’s a simple blood draw and is commonly done alongside cholesterol testing.

What to know:

• Healthy levels:
  • 3.0 or lower mg/L is considered lower cardiovascular risk.
  • Higher than 3.0 mg/L suggests an elevated heart disease risk and may prompt additional testing or monitoring.
• How to improve it: Lowering hs-CRP starts with calming the processes that drive inflammation. Consistent movement, better sleep and diet, stress management, and limiting alcohol or smoking help your immune system stay balanced and reduce inflammatory signals. Addressing underlying causes — such as infections, metabolic issues, or chronic inflammatory conditions — is often the most effective way to bring levels down over time.

25-Hydroxy Vitamin D

Vitamin D supports bone strength, immune function, muscle health, mood regulation, and metabolic balance. It’s unique among vitamins because your body can make it when your skin is exposed to sunlight, and you can also get it from food or supplements. However, low levels are very common, especially for people who work indoors, live in northern climates, have limited sun exposure during winter months, or have absorption issues.

This test measures 25-hydroxy vitamin D, the main circulating form in your blood and the most reliable indicator of overall vitamin D status. Tracking it helps clarify whether symptoms like fatigue, frequent illness, low bone density, or slower recovery may be linked to deficiency, or whether supplementation and sun exposure are adequate.

What to know:

• Healthy levels: Normal levels range from 20–40 ng/mL, with some experts aiming for 30–50 ng/mL depending on individual risk.
• How to improve it: Safe sun exposure when possible, vitamin D–rich foods like fatty fish and fortified dairy, and supplements when needed. Addressing metabolic health and absorption issues can also improve how your body uses vitamin D. Any high-dose supplementation should be guided by a clinician to avoid excessive levels. 

Vitamin B12

Vitamin B12 plays a major role in nerve health, brain function, and red blood cell production. It also helps your body turn food into usable energy. When B12 levels drop, symptoms often build slowly and may include persistent fatigue, brain fog, memory issues, mood changes, and tingling or numbness in the hands and feet. Because absorption can decline with age and certain medications, tracking B12 helps surface early neurological or metabolic strain before symptoms become harder to reverse.

What to know:

• Healthy levels: Typical reference ranges fall between 200–900 pg/mL, though ranges vary by lab. Levels below ~200 pg/mL suggest deficiency, while low-normal or borderline levels may still cause symptoms, particularly neurological ones.
• How to improve it: B12 can be increased through foods like meat, fish, eggs, dairy, and fortified cereals or plant-based alternatives. If absorption is limited, supplements or clinician-guided treatment may be needed to restore healthy levels and protect nerve function.

Hormonal health 

Testing testosterone, estradiol, DHEA-S, and luteinizing hormone (LH) helps show how well your body’s hormone system is communicating and responding. Each one plays a different role: LH acts as the signal hormone, testosterone and estradiol function as sex and metabolic hormones, and DHEA-S serves as an adrenal vitality and stress-balance hormone. Together, these markers offer a clear snapshot of hormonal balance—not just for fertility, but for long-term metabolic, cardiovascular, bone, and cognitive health.

Total testosterone

Testosterone is often talked about as a “male hormone,” but everyone has it—and everyone needs it. In men, it plays a big role in muscle strength, bone health, energy, mood, sex drive, and sperm production. In women, much smaller amounts are made by the ovaries and adrenal glands, but testosterone still supports bone density, libido, and overall metabolic health. Testosterone doesn’t work alone: your brain’s pituitary gland regulates how much you make through signaling hormones like luteinizing hormone (LH).

Most testosterone in your blood is attached to proteins, with only a small portion freely available for your body to use. When doctors check total testosterone, they’re measuring all of it together—free, loosely bound, and tightly bound—which is why it’s the first test used when symptoms appear. Levels naturally change with age: men tend to see a gradual decline starting in midlife. Testosterone levels in women gradually decline from around age 20-25 and don’t sharply drop off at menopause, unlike the abrupt decline in estrogen. Testosterone levels in women can be low and have no adverse effects; high levels are significant, however.

What to know:

• Healthy levels: Adult men typically fall between about 291-1100 ng/dL, while women are usually much lower, around 18-54 ng/dL. The lab will interpret results based on your age and sex. 
• How to improve it: Protecting sleep, managing stress, moderating alcohol, and maintaining steady nutrition and activity help keep testosterone signals stable. Strength training supports muscle and bone health, while avoiding extreme dieting or overtraining helps prevent unnecessary drops. For women, maintaining metabolic health, supporting adrenal function, and addressing cycle- or menopause-related changes are key. Testosterone can be added as hormone therapy in women, but it doesn’t have to do with the serum levels or changes during menopause, which affect estrogen and progesterone.
• Treatment: 
  • For men, when low levels are confirmed and symptoms persist, clinicians may consider testosterone replacement therapy (TRT). TRT is used selectively, monitored closely, and based on labs, symptoms, and individual risk factors.
  • For women, low testosterone levels don’t require treatment. Testosterone can be prescribed off-label for hypoactive sexual desire disorder (HSDD), but the diagnosis is clinical—not based on lab values. Testing testosterone levels isn’t needed before treatment. There are currently no FDA-approved testosterone therapies for women.

Estradiol (E2)

Estradiol is the most active form of estrogen, and it affects far more than reproduction. It plays a key role in how your bones stay strong, how your heart and brain function, how your body manages fat and metabolism, and even how steady your mood feels. While it’s often labeled a “female hormone,” estradiol matters for both women and men, and shifts in this hormone can quietly influence long-term health before obvious symptoms appear.

For women, estradiol levels naturally rise and fall during the menstrual cycle, then drop significantly in menopause. In perimenopause, levels can be very high, fluctuate wildly, and be unpredictable. With these changes can come hot flashes, sleep disruption, or shifts in weight and energy. 

For men, estradiol is made by converting testosterone into estrogen. Even at lower levels, it helps protect bone density, supports fertility, and plays a role in cognitive and cardiovascular health. Too little or too much, in either sex, can affect how the body functions over time.

What to know:

• Healthy levels: Estradiol levels vary based on sex, age, lab, and (for women) cycle timing, so results should always be interpreted in context rather than compared across different phases or life stages.
  • Adult men: 14–55 pg/mL
  • Adult women (premenopausal):
    • Follicular phase (around day 5): 19–140 pg/mL
    • Just before ovulation: 110–410 pg/mL
    • Luteal phase: 19–160 pg/mL
  • Postmenopausal women: Less than 35 pg/mL
• How to improve it:
  • For women: Nutrition, strength training, stress management, and sleep can support overall hormone balance and symptom management, but they do not replace estrogen loss. Working with a clinician helps determine whether HRT is appropriate and ensures levels stay in a healthy range.
• Treatment: For people in perimenopause and menopause, Hormone replacement therapy (HRT), when clinically appropriate, is the only effective way to replace declining estradiol. 

DHEA-S (DHEA-Sulfate)

DHEA-S is an adrenal hormone that helps counterbalance cortisol, your main stress hormone. Scientific analysis shows that when the cortisol-to-DHEA-S ratio stays too high, it signals chronic stress and is linked to muscle loss, cognitive decline, and faster biological aging. 

DHEA-S is produced primarily by the adrenal glands and serves as an important precursor for estrogen and testosterone in both men and women. It plays a role in metabolic vitality, immune modulation, and muscle maintenance, and helps the body balance the effects of stress hormones like cortisol. Levels naturally peak in early adulthood and decline with age, which is why DHEA-S is often used as a marker of long-term vitality. Because DHEA-S stays relatively stable throughout the day, it provides a consistent view of adrenal hormone production compared with many other stress markers.

What to know:

• Healthy levels: DHEA-S levels naturally vary by age and sex and tend to decline over time. Below are commonly cited adult reference ranges.
  • Females:
    • Age 18-44 60-407 µg/dL 
    • Age 45-74 9.4-256 µg/dL
    • Age 75-150 12-154 µg/dL 
  • Males:
    • Age 18-44 89-492 µg/dL
    • Age 45-74 33.6-331µg/dL
    • Age 75-150 16.2-123 µg/dL
• How to improve it: Because DHEA-S is made by the adrenal glands, improving levels means protecting adrenal health. Prioritizing consistent, high-quality sleep, pacing physical training to avoid overtraining, and reducing long-term psychological stress helps prevent long-term cortisol dominance that can suppress DHEA-S. DHEA supplements are not recommended without medical supervision, as they can disrupt hormone balance and cause unintended side effects.

Luteinizing Hormone (LH)

Luteinizing hormone (LH) is a key “signal” hormone made by the pituitary gland that tells the ovaries or testicles how much sex hormone to produce. In women, LH helps regulate the menstrual cycle and triggers ovulation. In men, it signals the testicles to produce testosterone and supports sperm production. Because of this, LH plays an important role in fertility, sexual health, bone strength, and long-term metabolic balance for both sexes.

When LH is too high or too low, it often means the brain–reproductive hormone loop isn’t communicating well. In women, fluctuating LH patterns are commonly seen during perimenopause, menopause, or with conditions like PCOS. In men, altered LH can point to low testosterone, fertility issues, or problems with the testicles or pituitary gland.

What to know:

• Healthy levels: 
  • In women before menopause, typical LH levels can vary by lab and range from 5 to 25 IU/L, with a brief spike around mid-cycle when ovulation occurs. After menopause, LH levels rise and usually fall between 14.2 and 52.3 IU/L. 
  • For men, normal LH levels are generally steadier, typically ranging from 1.8 to 8.6 IU/L. Reference ranges vary by sex, age, and (for women) cycle stage. Results are always interpreted alongside other hormones like FSH, estrogen, or testosterone.
• How to improve it: Luteinizing hormone (LH) is a signaling hormone; LH itself isn’t something you treat directly, but it gives valuable insight into your overall hormone balance.
  • For women, high LH usually signals low estrogen—common in perimenopause and menopause—while low LH can indicate reduced reproductive signaling from stress, under-fueling, or other factors. LH is also used in fertility workups because its surge triggers ovulation. Since LH often reflects what estrogen is doing, treatment focuses on supporting low estrogen when appropriate, which can help protect bone, heart, vaginal, and sleep health. Lifestyle habits like balanced nutrition, stress management, and regular activity also support the hormonal system that regulates LH.
  • For men, testosterone therapy is commonly used to restore energy, libido, and other sex-hormone–driven functions when fertility isn’t a priority. When fertility does matter, treatments may focus on stimulating the brain–testicle pathway with pulsatile GnRH or, in selected cases, medications like clomiphene.

Monitoring biomarkers gives you a path to a healthier you

These 17 biomarker-based health insights tell a single story: how well your body is aging on the inside. They show how your metabolism is handling blood sugar and fats, how your heart and blood vessels are coping with daily demands, how inflamed or calm your system is, whether your organs are under strain, and whether your hormones and nutrient levels are truly supporting you. Instead of guessing based on how you feel in the moment, you get a clearer map of where you are right now—and where small, targeted changes could have the biggest impact.

That’s the idea behind Noom’s Proactive Health Microdose GLP-1^Rx Program. It goes beyond one-off annual labs by pairing regular biomarker testing with low-dose GLP-1 support so you can see how your numbers improve as you adjust your habits, medications, and routines. 

Most importantly, you’ll see your results translated into clear insights. Over time, that means watching your biomarker trends shift in the right direction and understanding how those shifts connect to your daily choices. The goal isn’t perfection or chasing a single “ideal” number; it’s using these insights to add more healthy, active, and present years to your life—and giving you the tools and support to get there.